Dr. Khan said the CMAJ paper is intended to make physicians aware of the fact that they can no longer overlook diagnosing osteoporosis in their male patients. "That's the bottom line. We want to bring all the research we have to the forefront and we want to bring it to the desk of Canadian physicians."

The CMAJ paper supplements clinical practice guidelines for the diagnosis and management of osteoporosis published by Osteoporosis Canada in 2002. It provides a review and synthesis of the current literature on the diagnosis and management of osteoporosis in men.

Up until now, Dr. Khan said, doctors have underestimated even how common the condition is in men. One in eight men over 50 years of age has osteoporosis, compared to one in four women after menopause.

In their paper, the researchers describe which men are at the highest risk, how to diagnose and investigate the disease, and offer the most up-to-date information on treatment.

Dr. Khan is also director of the Calcium Disorders Clinic at St. Joseph's Healthcare in Hamilton, Ontario and director of the Oakville Bone Centre in Oakville, Ontario.

She said scientists are "just at the tip of the iceberg" in understanding the implications of osteoporosis for men, unlike women where it's well known which women are at risk, how the disease develops and how to treat it.

"The problem," she said, "is that when men sustain fractures they are more likely to die or suffer a disability."

Statistically, one in three men die following a fracture, compared to one in five women, possibly because of underlying health problems, such as heart disease, which make it difficult for them to cope with a fracture that could involve hip surgery, prolonged bed rest and rehabilitation.

Content posted January 30, 2007